Anastrozole aromatase inhibitor

Common Questions and Answers about Anastrozole aromatase inhibitor

arimidex

Avatar n tn December 14, 2009 (San Antonio, Texas) — New results coming from 2 mature trials with exemestane (Aromasin, Pfizer) suggest that this aromatase inhibitor differs slightly from the other 2 available products, letrozole (Femara, Novartis) and anastrozole (Arimidex, AstraZeneca). Although all 3 are aromatase inhibitors, exemestane is a steroidal product that binds irreversibly to the estrogen receptor; the other 2 products are both nonsteroidal and are reversible inhibitors.
Avatar n tn Please discuss with your treating doctors, the option of switching aromatase inhibitor therapy to one of the other agents, such as Femara (Letrozole) or Exemestane (Aromasin), to determine whether you would better tolerate these other drugs. I wish you well and I hope that something can be done to alleviate your discomfort....
Avatar n tn Thanks for your response. Most of the problems I have had are listed as side effects on the pharmacists notes that I have received. You are right. It is not possible to absolutely link any of my problems to the drug, but I am sure enough that I am just about ready to discontinue it to see if things improve.
Avatar f tn To evaluate the efficacy and toxicity of the selective aromatase inhibitor anastrozole (Arimidex), we conducted a phase II trial in 53 women with asymptomatic recurrent/persistent müllerian cancer. METHODS: Patients with ovarian, peritoneal, or fallopian tube carcinoma were eligible for enrollment. Eligible patients had an ECOG PS 90 days, 15% for >180 days, 7% for >270 days, and 4% for >360 days. One patient remained on anastrozole at 15 months.
Avatar f tn Dear river1980, Both Femara (letrozole) and Arimidex (anastrozole) are aromatase inhibitors used in the treatment of hormone receptor positive breast cancer in post menopausal women. Aromatase inhibitors block the enzyme aromatase (found in the body's muscle, skin, breast and fat), which is used to convert androgens (hormones produced by the adrenal glands) into estrogen. In the absence of estrogen, tumors dependent on this hormone for growth will shrink.
Avatar n tn I will be doing 30 days of radiation to the breast, not including the nodes, and at the same time will be taking an aromatase inhibitor (hormone) which previously reduced my tumor over 55%. The numbers show that hormone therapy will add a 17% advantage and chemo will give me "only" a 4% advantage; so the question is, is it really worth all the negatives of chemo for a 4% advantage?
Avatar n tn Her cancer was both progesterone and estrogen receptor positive. Another blogger asked the question about the wisdom of taking an aromatase inhibitor with little or no breast tissue remaining. There are studies of mortality and cancer reoccurence after using these drugs, but her oncologist could site no specific results of women who had bilateral mastectomies. Do you know of such a study? Additionally, there are many side affects of these aromatase inhibitors.
1030058 tn?1252253572 (beyond the initial 5 years) is with letrozole (Femara) after 5 years of tamoxifen. Letrozole and anastrozole (Arimidex) are both aromatase inhibitors and are very similar to one another. In most of the adjuvant studies using these drugs, 5 years of treatment has been given. An ongoing study will compare 5 to 10 years of aromatase inhibitors but there are no results available yet on that study.
Avatar n tn If I get the testosterone shots, how likely is it that I will have a large portion of it converted to estrogen given the fact that my current level is low. Should I consider taking a aromatase inhibitor as a preventative measure for testosterone shots. My doctor said we could discuss the shot at my next appointment and I'm wondering if it would be a good idea to ask for aromatase inhibitor.
962875 tn?1314210036 If women are treated for 2 years with tamoxifen, such individuals may develop cognitive dysfunction which can reduce their quality of life prior to the time at which they would switch to an aromatase inhibitor. In contrast, women who initially receive aromatase inhibitors would not be expected to have to suffer from such cognitive dysfunction.
Avatar m tn I went for a year and a half before my levels showed I was menopausal.
Avatar m tn Hi, In regard to your question regarding of continued use of tamoxifen (past 5 years) vs switching to an aromatase inhibitor, this recommendation was put forth in 2110: "A leading group of cancer experts has issued new guidelines on the best way to use two classes of hormone therapies for estrogen receptor-positive breast cancer, the most common form of breast tumor.
Avatar m tn Dear madwilson, Hairloss is not a usual side effect associated with Arimidex. Arimidex is an aromatase inhibitor. This means it blocks the enzyme aromatase (found in the body's muscle, skin, breast and fat), which is used to convert androgens (hormones produced by the adrenal glands) into estrogen. In the absence of estrogen, tumors dependent on this hormone for growth will shrink. For more information regarding this drug and side effects you can check out the website chemocare.com.
Avatar f tn It has been recommended that I have Hormone Therapy, probably aromatase inhibitor.. My question is.. would you recommend radiation therapy? thank you for your time...
Avatar f tn There are several that you can google. Femara, Aromatase, Aromasin, and Tamaxifen. Some of these inhibitors are also for Breast Cancer. Sorry if my spelling is wrong. There is another inhibitor called Avistan (not for hormones). Hope this helps...
Avatar n tn However, if you have had your ovaries removed, then you would be postmenopausal and could possibly take an aromatase inhibitor instead of tamoxifen. Either way, if your breast cancer is hormone receptor positive, then hormone therapy would likely be recommended as the body does produce estrogen outside of the ovaries. You should discuss with your doctor what drug might be best for you.
135691 tn?1271097123 At The Mayo Clinic I asked about switching to another aromatase inhibitor should the Femara stop working and they said that Femara is one of the stronger aromatase inhibitors so if it stopped working they would try another theraputic approach because they didn't think switching to another aromatase inhibitor would help much.
Avatar n tn Dear Char214: Femara is an aromatase inhibitor, it works by blocking the enzyme that converts the body's androgen hormones into estrogen. This type of treatment is one of the appropriate hormone (anti-estrogen) treatments of estrogen receptive breast cancer in post-menopausal women.
1162347 tn?1293503170 In December 2004, the American Society of Clinical Oncology (ASCO) issued new guidelines on hormonal therapy. ASCO now recommends that most postmenopausal women be treated with an aromatase inhibitor. This means that tamoxifen, which first began to be used in the adjuvant setting in the 1980s, is no longer the standard of care for postmenopausal women.
Avatar m tn I will be undergoing an ooferectomy as a precaution, as my mother died of ovarian cancer at the age of 59. The plan is to put me on a aromatase inhibitor about 1 week after my surgery. My question is: is the oopherectomy a good plan for me, considering my background? And also, is an aromatase inhibitor necessary given the fact that my ovaries will be removed? I was diagnosed with a 2.5 cm tumor with calcification totally 4.5cm. Stage 2A/grade 2 with LVI-lymphatic vascular invasion.
Avatar f tn On the other hand knowing that the tumor was quite receptive to both estrogen and progesterone helped me to accept the aromatase inhibitor prescription given to me by my oncologist. The test suggested that the benefit of that treatment would be quite high. I have been taking the aromatase inhibitor for about a month now with relatively minimal side effects.
Avatar m tn Now endo is suggesting that in order to give him more time to grow, we give him Anastrozole. I have seen lot of posts and spent hours on the forums wherever I found mention of advanced bone age/Anastrozole/Letrozole. It seems there are quite a few posts under Pediatric Endo forum but not able to find any answers if any parents tried Anastrozole/Letrozole and what has been their experience regarding delaying bone age and side effects.
Avatar f tn HRT usually means hormone replacement therapy. Was your tumor estrogen or progesterone positive? After a breast cancer diagnosis female hormones are generally avoided. If you don't have chemo (oncotype dx recurrence score of 8% is low) the usual recommendation is an AI (aromatase inhibitor) 'estrogen blocker' such as Aromatase or Arimidex.
Avatar f tn I have the same experiences and the same answers from my Open Access nurse, these are not typical side effects to your medication.
Avatar f tn I've had three cancers, all estrogen positive. I tried a few medications and I'm now on Aromasin, an estrogen inhibitor. I figure I'll try the Aromasin and see if it gives me more protection from a recurrence. It's the least debilitating of the aromatase inhibitors for me, but it does cause joint pain. It's in clinical trials right now for ovca, but I am NOT waiting for the results of the trial.
Avatar f tn I'm on a newer member of the aromatase inhibitor family: Aromasin. It suppresses the release of estrogen. Aromasin is in clinical trials for ovarian cancer at the moment, but I'm not waiting for the trials to be over. It took only a few months to lower my estradiol, which is at a negative 20 right now. My cancer(s) were all estrogen dependent. Oddly enough, though, not all female cancers are estrogen dependent, so have your friend check to see if hers was.
587083 tn?1327120262 If you are already postmenopausal, an alternative to tamoxifen is an aromatase inhibitor. Again, it will be hard to predict whether you will have an allergic reaction to this type of drug. Have you been seen by an allergologist? I would suggest consult with one. You oncologist can also work closely with your allergologist when you are being given your medicines. Take care.
Avatar n tn Have developed a heart rhythm disturbance, shortness of breath, edema of hands and legs/feet since being on Anastrozole. How worried should I be? Should I consider discontinuation discussions with my Dr.? This discussion is related to <a href='/posts/show/542261'>Can Arimidex Cause Skin Lesions?</a>.