Hi, the condition strongly suggests angioedema which is due to hypersensitivity reaction (type 1). Drugs like
amoxicillin, certain painkillers like aspirin,
ibuprofen, certain garments, environmental allergen and certain food (fish, mushroom, peanuts, soy etc) can cause such reaction.
In your case, the allergic reactions seems to be secondary to ibuprofen and you should avoid further exposure.