Ammonia toxicity mitochondria

Common Questions and Answers about Ammonia toxicity mitochondria

ammonia

Avatar f tn she has continued to take the Lactolose for the past two weeks but today her ammonia level is 150. I would like to find out how high ammonia level can go before it is considered toxic and will cause her to go into a coma? I am also wondering in end stage cirrhosis will the lactolose eventually be uneffective in bringing down the ammonia levels? My final question is what kind of life expectancy is there when the cirrohsis remains at that level?
395787 tn?1298428787 could anybody please tell me what actually mitochondria is an what happens with axonal outgrowth and how it affects the body with thanks
Avatar n tn According to what you posted, he was diagnosed with Angelman Syndrome - which is a genetic disorder. There is no cure. From the symptoms you describe, that seems to fit. Other than physical therapy and other care that is similar, I don't really have any other ideas.
Avatar m tn many myofibers contained large collections of mitochondria in the subsarcolemmal regions, several myofibers were small and atrophoic, one example of ringbinden. Mitochondria were normal in size and appearance. 1999: Histochemistry was normal. Myoglobinuria Myopathy Profile and Glycogen Storage Myopathy A panel from Athena Diagnostics were normal. Mitochondrial enzyme profile were normal except for an increased level of citrate synthase (20.21 vs a reference range of 7.33-12.43).
233616 tn?1312787196 Cytochromes are colored with iron. Cytochrome P450 is located on the inner membrane of the mitochondria of liver cells (the mitochondria is the powerplant of the cell...it stores oxygen to power the cell). CYP450, is a target of the hepatitis C virus. The virus gets help from CYP450. Why does HCV target the mitochondria? Because the mitochondria is the location of the interferon response mechanism. By damaging the mitochondria, the Hep C virus stops the interferon response.
Avatar f tn ~~ @@@Center for Human Reproduction offers patients who are above 40 and for those, who suffer from low levels of AMH, an innovative program that makes it possible to get pregnant with their own eggs. Mitochondria replacement therapy is an innovation and a breakthrough in the field of ART and the fertility treatment.
1008841 tn?1293598960 In terms of diet, I believe you should be avoiding as much salt as possible, and at least for the short term, reduce animal proteins to avoid complications of ammonia toxicity. Try to limit your protein intake to things like legumes and soy products; they are less likely to metabolize into ammonia in your gut. Protein is an important component of your diet though; be sure to confirm any info you gather here with your doctor.
Avatar m tn For two years i have been dealing with a neurologist and a metabolic doctor who both diagnosed me with mitochondria however my muscle biopsy results came back saying i did have features of mitochondria but not ones good enough to say this is whats effecting my walk.So the metabolic doctor said she would not be able to help me and that i didnt have mitochondria but the neurologist thinks different.
Avatar m tn The premise of most pathophysiologic theories involves the accumulation of ammonia in the central nervous system, producing alterations of neurotransmission that affect consciousness and behavior. These ammonia toxicity theories have been supported by studies demonstrating increased ammonia levels in patients with both fulminant hepatic failure and chronic liver disease.
Avatar m tn which is worse, potential resistance, or possible kidney damage and mitochondria damage? tenofovir is the least damaging on both, studyforhope pointed out already that tenofovir is the safest on this, as regards kidneys hbv patients have lowered kidney function from entecavir more than tenofovir and only those with damaged kidneys before starting antivirals.
1479013 tn?1330699762 This can happen in certain chronic conditions where mitochondria are stressed. Unfortunately, in many chronic conditions our mitochondria are stressed, and especially when intracellular infections are present that cause oxidative stress to our mitochondria. (The cardiolipin molecules in the inner mitochondrial membrane are expecially sensitive to excess oxidative stress and once oxidized they can be released from cells.
317787 tn?1473358451 or is it only the lactulose that removes the ammonia? I appreciate any advice. I see the doctor on May 1st and will also talk to him.
Avatar f tn uk I have read so many articles about CFS that detail possible causes and proposed treatment plans, but no other doctor had illustrated, step by step, just how the mitochondria in our cells make energy so that they can function. She explains it all very clearly, although it is a complex bio-chemical process. I still don't know what caused my mitochondria to malfunction in the first place, but at least now I understand what I'm doing to my body when I PUSH myself through my day.
374652 tn?1494811435 Monitoring of food consumption, gain in body weight and physical observations did not reveal any treatment-related toxicity in any of the group of rats. Terminal autopsy also did not reveal any signs of toxicity. Further, no significant alterations in relative organ weight, serum biochemistry and urinalysis were observed up to 1% lactulose supplementation level. The results suggest that supplementation of lactulose in the diet does not produce any toxicity at the doses tested.
Avatar m tn Anti-mitochondrial antibodies (AMA) are autoantibodies, consisting of immunoglobulins formed against mitochondria,[1] primarily mitochondria in cells of the liver. The presence of AMAs in the blood or serum of a person is indicative of several autoimmune diseases such as primary biliary cirrhosis (PBC) (a scarring of liver tissue, confined primarily to the bile duct drainage system of the liver). It is present in about 95% of cases.
Avatar f tn I'm 6 weeks pregnant and I work in a paint department. I mix colors and clean up paint pretty much. Since I've worked there we have always used glass cleaner to clean the paint off the desk and our hands. I didnt know this until today but the cleaner we use has ammonia in it. I've been using it every day for a few months to get the paint off of my hands. Could it have hurt my baby?
Avatar n tn We discovered that my husband had an episode of Encephalopathy, which is high ammonia in the blood. But by the time we had his blood checked his levels were right smack in the middle of the range. Doctor said he was fine. So my question is can this ammonia gone untreated continue to rise and lower on its own. Because he has days that he seems fine and then days when he is not with me completely. He does not eat much as his taste buds are totally out of wack. Most foods taste very salty.
Avatar f tn I recently found out I had high ammonia, it was 66, I am taking lactalose and it is is now normal. All my blood work is within normal ranges on my liver function test and I also had a sonogram, have a mild fatty liver. Was wondering what could have caused this. I do drink a few beers a night.