Ammonia levels of the body

Common Questions and Answers about Ammonia levels of the body


An ammonia test measures the amount of ammonia in the blood. Most ammonia in the body forms when protein is broken down by bacteria in the intestines. The liver normally converts ammonia into urea, which is then eliminated in urine. Ammonia levels in the blood rise when the liver is not able to convert ammonia to urea. This may be caused by cirrhosis or severe hepatitis. Since you are on this forum I assume you have hep c? Are you experiencing the effects of toxic buildup in your blood?
A little bit further down the article explains that ammonia levels do not necessarily correlate with the symptoms of encepalophy. I hope this helps.
10 to 80 mcg/dL Your liver may not work properly if you have high levels of ammonia in your blood. Ammonia is a chemical made by bacteria in your intestines while you process protein. Your body treats ammonia as a waste product. It turns it into glutamine and urea. Then the urea travels to the kidneys and is eliminated in your urine. Ammonia will build up if the liver is too damaged to get rid of urea. This can sometimes happen if you have advanced liver disease.
He has had high ammonia levels as high as 420. He has been in the ICU because of this. He also takes lactulose to keep the ammonia levels down. My question is....he smells. It is the ammonia leaching from his body. We recently changed deodorants because they were turning his underarms black. Is there anything we can do to help decrease the smell? Natural laundry soap for clothing and bedding? Please help, we love him very much, but the smell is just horrible.
He has been in and out of the hospital for the fluid filling up in his stomach and they have to drain it. He has been back and forth to the hospital because his ammonia levels get high and he gets very disoriented. He is on Cobra now because he has to be on SS disability for 2 years before he gets medicaid. But we're afraid that he's reached is max on his insurance now and people are telling us if he does there's no way they'll do a transplant if you don't have insurance? Is that true?
This leads to adverse effects on the brain. By acidifying the contents of the gut, lactulose reduces the absorption of ammonia from the gut, therefore preventing the adverse effects experienced by people with liver disease." Hope this is helpful. How are you doing? Is the ammnoia causing you problems or did the doc find it in your blood work but you dont have symptoms from it?
When these waste products are not expelled from the body, they create the product of ammonia. Too much ammonia can lead to disorientation and swelling of the brain. If your problem is liver related, you will need to go to a gastroenterologist for exam and bloodwork to measure what is in your blood - including ammonia levels and your liver enzymes. I have had a liver biopsy 2 years ago and found out I had the cirrhosis.
Nothing looks out of whack though, except the ammonia. Anything out of all of this, esp all of the meds and lifestyle behaviors, dehydration provide any clues?? Also, have been losing weight since mid-Feb...28 lbs...doing it not too drastically though, and have been feeling ok w/exception of late May/early June starting feeling very lethargic for awhile...prob a sign of the high ammonia levels.
My father has cirhosis and we have been dealing with high ammonia levels. He has confusion and weakness. He is on Lactulose and an antibiotic. I am reading a lot about a low/no protien diet but a few posts say a high protien diet is recomended. Can I get clarifiation and any tips on what to eat and not to eat? Thanks in advance!
I am fairly confident that the high ammonia levels are a result of the liver not working . the liver can fix itself to a point, alcohol will destroy it to the point of not being able to repair itself. everybody reacts different to the ammonia levels, my mother;s level was at 220 and she should have been comatose, but wasn't.. are they giving him the lactalose to lower the levels?
Since then, he's been in and out of the hospital, with out the discovery of exactly what it is that he has. However, recently he's been having episodes of confusion,and yesterday was barely able to wake up. He's in the hospital now, and they found his ammonia levels at 200. It comes and goes, but it seems that when he is the best is when he takes lactulose, and hopefully they'll raise his dose of it, because it just seems to be getting worse.
In patients with advanced cirrhosis, the liver is no longer able to metabolize the ammonia and convert it to urea so the ammonia builds up the in body producing and travels to the person's brain with psychological and other effects.
Also for the last 2 years I continue to retain massive amounts of water Here's the wierd part, the left side of my body gets huge from water but the right side gets huge from my liver disstending,I still get water weight on the right also. My left ankle goes from a 7 1/2 in. to a 15 in.monstrosity. I have had 4 tx's for hepc with no positve results. The last one was pegesus. I aam in pain always and I feel as if the docs don't know any more than my 9 yr old does.
Person with HE need to avoid red meats as it will increase the amount of ammonia in the small intestine which will travel to the brain. Good luck in quitting alcohol.
What I don't understand is how he can have an ammonia level of 280 with so many bm's a day. The purpose of the bms is to eliminate the extra ammonia/toxins. Doesn't make sense. Your doctor is right about how he feels is more important than a number. If he is able to speak to you coherently and understand what is being said to him and respond appropriately, then his HE is under control. Does he have other symptoms of decompensation like ascites and esophageal varices.
Eating a lot of sodium can also cause elevated ammonia levels in the blood.
Cindy, 21-50 micromoles per liter (mcmol/L) is the normal range depending upon the lab you use. Higher than norm ammonia levels are usually due to a problem with protein being broken down in the small intestines. It is then process by the liver and eliminated through the kidneys in your urine. So any problems in this part of the digestive system can result in higher than normal ammonia level.
The ammonia level is tested primarily to investigate behavior changes and changes in consciousness in adults such as mental changes, disorientation, sleepiness, or lapse into a coma. An ammonia level is also done to detect and evaluate the severity of a urea cycle defect. The normal adult values are 15-45 micrograms per deciliter (mcg/dL) which can vary from lab to lab. If you have higher values than normal, then the body is not effectively metabolizing and eliminating ammonia.
If the liver is decompromised it cannot metabolize the waste products hence there is an elevation of blood ammonia levels resulting in increased excretion in the urine. Also, increased levels of ammonia may also be seen with gastrointestinal bleeding, where the blood cells are haemolysed in the intestines, releasing protein. Please discuss this with your doctor am sure he will provide further assistance. Hope this helped and do keep us posted.
The interpretation of migraines as the cause of the tiny lesions on MRI are only suggestive and are not absolute. The lesions are probably non-specific and could have been caused by other conditions. Hope this answers your query.
Bacterial decomposition of the apocrine sweat produces the characteristic adult body odor unique to the individual. Do not mix this up with regular sweat from exercising. Ammonia odors from the breath or body sweat are called uremia. Nitrogen containing waste products, often from failing or damaged kidneys are suspected. Kidney tests are recommended to rule this out.
Shelley, the lactulose is really essential for managing your digestive tract and minimizing the build up of ammonia and other toxins. The higher the ammonia level, the more severe the HE, and the more severe the HE, the more difficult it will be for you and your liver doc to manage your liver disease. You have to control the HE, so that you can manage your meds, your diet, and other aspects of your liver care. Please don't skip your lactulose.
(forgetfullness) We changed to a mostly vegan diet because the animal proteins in meat and dairy products produce the ammonia problems. He also takes a few sips of lactulose during the day which I also understand to be very good and helpful. Since making these changes I've not seen anymore symptoms. I know your situation is far more severe but I thought I'd offer what little I could as help.
He presently takes Lactulose, but has been hospitalized in the past to help with the high ammonia levels. A low protein diet sometimes helps with ammonia levels, but not always. The only thing that has recently helped my brother with symptoms is the "Alzheimer's patch." I won't mention the name of the medication or the pharmaceutical company, and no--I'm not a rep for the company. It is being used off-label by my brother's doctor and his quality of life has improved dramatically.
It really is our only defense against the high ammonia levels. I take 8 to 16 shot glasses per day. I hate the taste of it and I can't stand the texture of it, but the alternative is worse.
just wondering if anyone has ever experienced this before jot any ideas...,,maybe someone has heard of this...I am beeing treated to high levels of acid in my blood...but she says (kidney Dr.) that this doesnt sound like anything with that...drs...i guess i havent found the right one huh!! take care love ya all... any ideas on what this could be....???
Mine were 108 when I started on lactulose a medicine that helps to take the ammonia out of the body. Are you having symptoms of hepatic encephalopathy? Are you confused?..having trouble with words?..or driving?
I have never heard of a drug that raises ammonia levels. The healthy liver processes the ammonia that is created in the gut so anything that would create ammonia normally would be eliminated by the liver. Good luck at the doc's.
His reason being that there is a chance of some of the chemicals entering the blood stream and the liver having to deal with them. He also recommended that I stop painting my fingernails for the same reason... nail polish remover doesn't just go through the polish. The main reason of doing tx is to save our livers, which filter everything we eat, drink, and get on our skin. If I were you, I'd ask my doctor to be on the safe side.
This can occur at the late stages of liver disease as the liver begins to fail more and more and is unable to clean the blood of toxins as it does in a healthy person. Ammonia levels do not always correspond with HE. 75 is not that high. I have ammonia levels that high on a regular basis. Then again I'm sure many on this forum thinks that explains a lot. Vomiting blood due to varceal bleeding in also a common common complication of ESLD.
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