Alendronate renal impairment

Common Questions and Answers about Alendronate renal impairment

fosamax

Avatar f tn These dosing interval recommendations are based on modeling of single-dose pharmacokinetic data in non-HIV and non-HBV infected subjects with varying degrees of renal impairment, including end-stage renal disease requiring hemodialysis.
Avatar f tn New Onset or Worsening Renal Impairment Tenofovir is principally eliminated by the kidney. Renal impairment, including cases of acute renal failure and Fanconi syndrome (renal tubular injury with severe hypophosphatemia), has been reported with the use of VIREAD [See ADVERSE REACTIONS]. It is recommended that creatinine clearance be calculated in all patients prior to initiating therapy and as clinically appropriate during therapy with VIREAD.
Avatar m tn It is likely the patient had acute colchicine toxicity brought on by the addition of erythromycin and superimposed on chronic colchicine intoxication secondary to renal and hepatic impairment. The patient improved with supportive therapy and intensive hemodialysis and was discharged on day 70 of hospitalization. Another report describes two fatal cases of agranulocytosis due to presumed interaction between colchicine and clarithromycin, a potent CYP450 3A4 inhibitor.
Avatar m tn Is this renal impairment reversible once I finish treatment? Any help would be most appreciated.
1128488 tn?1265053382 AMPYRA is contraindicated in patients with moderate to severe renal impairment (CrCl≤50 mL/min); the risk of seizures in patients with mild renal impairment (CrCl 51–80 mL/min) is unknown, but AMPYRA plasma levels in these patients may approach those seen at a dose of 15 mg twice daily, a dose that may be associated with an increased risk of seizures; estimated CrCl should be known before initiating treatment with AMPYRA." (http://brassandivory.blogspot.
Avatar m tn 96 and now at 1.43. He has no renal impairment and his kidney ultrasound and detailed urine report is perfectly normal. He is cirrhotic (Hep-c) at stage 2 according to doc (hep-c) which stopped the sovaldi + ribavirin treatment to save his kidneys. However during the period he was also on diuretics (furosemide) occasionally. His nephrologist says that it is safe to continue sovaldi treatment but the other doc gave a red flag (I have yet to have a dicussion with the nephrologist).
Avatar n tn Seven patients, of whom five were hepatitis C positive, developed renal function impairment long after transplantation, as well as de novo nephrotic syndrome (n = 5), severe hypertension (n = 5), nephritic syndrome (n = 1), and increased serum creatinine (n = 1). This type III cryoglobulinemia was associated with membranoproliferative glomerulonephritis and with thrombi within the glomeruli in one case.
Avatar m tn Persistent increased level of serum creatinine or decreased level of urine creatinine usually reflects impairment of renal functions. Here are some natural ways for lowering high creatinine. http://www.kidney-cares.org/creatinine/100.html http://www.kidneyfailureweb.com/creatinine/233.
1471082 tn?1286757000 Swelling of legs could be due to osteoarthritis, hypertension, renal impairment. So please consult your treating neurologist to have a look and refer you or suggest you to consult an orthopaedician if required. If he is already not taking, he may require treatment for agitation or aggressive behavior. Hearing aids, glasses or cataract surgery if appropriate. Behavior therapy might help by ignoring inappropriate and rewarding good behavior. Reality orientation may help reduce disorientation.
Avatar f tn While elevated ammonia levels are seen in cirrhotic patients there can be encephalopathy with normal ammonia levels and there can also be no mental impairment in some patients with elevated ammonia levels. Basically, ammonia levels are of limited use for diagnosing cirrhosis or hepatic impairment. I would also think some other results of your blood work would have been out of range if you are cirrhotic or are suffering significant liver impairment.
Avatar m tn An elevated BUN [blood urea nitrogen] is concern for liver and/or renal impairment, not diabetes. Although I have empathy for your father, you are seeking help in the wrong place. Ask your father's doctor to refer you to a nutritionist or some who specializes in that degree in your country.
Avatar f tn I took my first dose of Alendronate and then experience significant muscle pain for the next 4 days. Does anyone know if I should expect this to happen each time I take it or is it something to happen for the first few times until my body adjusts to the medicine?
Avatar n tn Do you mean Fosamax (alendronate)? If you do, its for treating bone problems like Osteoperosis by adding bone mass and slows bone loss. I use it for Osteopenia.
Avatar n tn Hi, Fluid retention can be due to various reasons like heart failure, low serum protein, renal failure, liver failure etc. Your father needs to get evaluated for the above mentioned causes to find out the cause for fluid build up in your father. Depending upon the cause treatment varies. Dobutamine is a inotrope, as a support in the short-term treatment of cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures.
Avatar n tn If these levels are unavailable (because the patient has been well and has had no blood tests) it is occasionally necessary to treat a patient briefly as having ARF until it has been established that the renal impairment is irreversible.
Avatar m tn The amount of mannitol in Copaxone is small and absorption Gabapentin (Neurontin) should be used carefully in patients with renal impairment due to possible accumulation and toxicity. It has been linked with liver toxicity. Provigil is metabolized by the liver and excreted in the urine. Have they looked for an independent cause? Some simple blood and urine tests can provide a lot of information about kidney function and possible causes.
Avatar m tn Patients should NOT be using any type of NSAIDs due to an associated increased risk of bleeding, renal impairment, and the development of diuretic-resistant ascites. Generally speaking Tramadol as an opioid pain medication can be problematic so better alternative should be looked into. It is also combined with acetaminophen which is high doses can cause additional damage to the liver. "ULTRACET contains tramadol HCl and acetaminophen.
Avatar f tn The elimination of the major metabolites of bupropion may be affected by reduced renal or hepatic function because they are moderately polar compounds and are likely to undergo further metabolism or conjugation in the liver prior to urinary excretion. Hepatic The effect of hepatic impairment on the pharmacokinetics of bupropion was characterized in 2 single-dose studies, one in patients with alcoholic liver disease and one in patients with mild to severe cirrhosis.
Avatar f tn s worst side effect is the development of a debilitating, and sometimes deadly, disease called nephrogenic systemic fibrosis or nephrogenic fibrosing dermopathy in people with impaired renal function. But there have been anecdotal reports of people with no known kidney problems developing NSF/NFD after gadolinium use.
Avatar m tn my father is a post liver transplant patient. almost an year has pased .Now along with all he has got renal impairment problem. His cretanine is almost 1.4 or around. My question is that should he continue his TACROLIMUS tablets or should switch to some other tablets which are safe for kidneys? Secondly , in my sorrounding there is an opinion that lowering the TACROLIMUS dose also let the liver enzymes to increase?
17402552 tn?1456364357 The specific gravity suggests partial impairment of renal function. Increased creatinine from one test to another suggests something is going on, very likely with the kidneys. BUN is only just at the upper limits. Your dog is very young to have developed kidney issues, therefore this may be connected with something she has eaten or with being dehydrated (possible) or with a genetic problem that has triggered. Time will tell.
Avatar m tn The prescription drug Fosamax (the generic is alendronate sodium) is a medication which has been prescribed to hundreds of thousands of postmenopausal women to treat osteoporosis and help increase bone mass thereby reducing the chance of spinal or non-spinal fractures. Fosamax has also been prescribed to increase bone mass in men with osteoporosis. Brand name Fosamax is manufactured in the United States by Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.