acyclovir resistant hsv encephalitis

Awaiting another derm appt.Took acyclovir for a few years prophylactically as occurrences are 3-4 times per month. Went off meds (worry about long term effects) and just bore with it for a few years. Then recurrences became very frequent and it is the pain prior that is most difficult - I get severe pain in my head, and behind my eye. The pain is debilitating. I recently began taking Valtrex 500 and it has helped enormously but I have some questions.

does recurrent hsv 2 infections also trigger radiculitis or sacral neuropathy or menigitis? what is the likelihood of developing hsv encephalitis or meningitis during recurrent attacks? is the neurologic manifestations exclusive only during the primary infection? does taking anti-virals (acyclovir, valacyclovir) decrease the neuropathic complications or no effect at all?

I have the HSV-1 virus and was doing some research on how the virus can be reactivted during brain surgery. I have posed this to my Neurologist and she prescribed Acyclovir (400 mg 5x/day orally). She precibed it for 14 days. I have taken it for five days with no results. If this were to be effective, would the recovery signs start to show by now? What is the normal length of time, in this cae, to kill the virus and be effective?

No, having an outbreak on antivirals isn't all that unusual. It does stop them entirely for some people, and in others, it just reduces them. It's still possible to get outbreaks while on them. I wouldn't worry about resistance, or the medication not working any longer. Maybe you have a trigger that you don't know about? Is it cold where you are, or maybe you're eating something that's triggering it? Have you been sick - the flu or a cold? Really stressed or fatigued?

I never saw obvious blister, so never got swabbed. I was started on Acyclovir for 10 days and then switched to Valtrex 1 gm twice a day. The fever stopped. But the itching and burning remained, and spread to all over the body. In March, my eyes started itching and pain. My eye MD did not see any lesion in the cornea, and prescribed artificial tear and anti-allergic drops, which were of little help.

They showed us the tubes of csf, which was as clear as water. My brother is hoping that this is hsv encephalitis, but has not done any research online, so he doesn't realize how bad that can be. Question 1: During the brief stay last month, the doctor put him on acyclovir i.v. for approx 12 hours. If only for that short a time, is it possible that it could have an effect on hsv encephalitis? Question 2: Would the csf appear clear if a virus is present?

Just wondering if genital herpes (HSV 2) can become resistant to valtrex over time. Been on it daily nearly two years and just had only my second outbreak. Not a bad one, but one none-the-less. Some things I've read indicate that this is possible. I'm certainly hoping that's not the case. Thanks.

Can the reactivation of HSV-1 cause a hemorrhagic stroke (burst of cavernou hemangioma)? Are there any tests that can be done to show this? My Neurologist has done an MRI of the brain, but she says my deficits are from the stroke. After over three years and no progress, I'd like to explore this possibility, especially since many things worsen right before menstruaion. Thank you for your time!

Seems to me acyclovir wears off during the night v lasts longer... Had a previous prescription. No test for bacteria infection, but always gets this way. Very careful about keeping clean and not touching.

First, it is rare for herpes to change its recurrence pattern. An increase in frequency of symptoms usually isn't herpes. Second, herpes never recurs as frequently as you seem to be experiencing. Third, it is very rare for herpes to become resistant to treatments like acyclovir; failure to improve is evidence against herpes as the cause. This isn't definite. Herpes can become resistant to acyclovir.

It is not usual to be resistant to acyclovir, it doesn't attack the virus directly, but removes the building blocks of the virus. It may be that you have another immune issue. People with thyroid issues for example can experience ongoing outbreaks. Is your diet healthy? Are stress levels up? I'm not a fan of supplements as I don't believe they substitute or add to the positive properties of a good diet.

In addition, the symptoms you describe do not suggest genital herpes, which does not cause the vague sorts of things you mention. I find it interesting that you took acyclovir during your sexual relationship with your HSV-2-infected partner. No knowledgeable provider would prescribe it in that fashion; there are no data to show it prevents transmission when the uninfected partner takes anti-herpes therapy. (Logically, it probably would help, just no data available.

I would like to go through basic std investigations...let me Knw the investigations...

1) Does preexisting HSV-2 definitively protect you against HSV-1? Does it matter where the HSV-1 is located; i.e. oral or genital? I am afraid to kiss this guy because of the severity of my HSV-2 symptoms. I cannot imagine what having oral HSV-1 on top of my genital HSV-2 would be like given that my HSV-2 symptoms are so severe, constant and uncontrollable (see below). If the answer is yes, PLEASE direct me to studies so that I may further educate myself.

I have been diagnosed with HSV-1 for as long as I can remember. Based on my life experience, this is an opportunistic viral infection. Every time I'm in the sun too long, I get "sun poisoning" (a cold sore) on my face. Every time I get sick and my nose runs, I get cold sores "in" my nose and on my philtrum? (area between nostrils and upper lip). On average I have a cold sore on my face at least 1 week a month. I take acyclovir PO and topical zythromax.

t avoid thinking of it please doctor i have 5 questions about it .Does HSV-1 can cause encephalitis???what is the risk of encephalitis how much that happen??How can i avoide that?? is there any vaccine to prevent encephalitis???

Second, it is almost impossible for herpes to not undergo substantial improvement within 2-3 days after starting an antiherpetic drug like acyclovir, and 7 days is far too long. HSV can be resistant to these drugs, but that occurs almost entirely in people who have been taking the drugs for a long time, typically for many months. And it's usually limited to people with severe immune deficiency, like AIDS, cancer chemotherapy, etc.

I am wondering if what I am describing as a chance of herpes? If I am on dailly acyclovir does that help me with resistant of HSV2 infection? Keep in mind I do have a high anxiety of herpes and HIV. What would be the next step since my sore is almost healed? If it is herpes what are the chances I received this from the friend 5 weeks ago or the girl im dating last week. Thank you Thank you for your time.

(I understand that this is the dosage for an episode, but she told me to take it 3-times a day everyday as suppressive therapy). From what I can tell, the Acyclovir is having little effect on my HSV-1 symptoms--preventing or treating them. (1) Can you recommend any experts or specialists in Boston?

thanks for the input. since i have had a positive culture, and have an obvious lesion with each ob, i am pretty confident that hsv is my issue. it's possible i have other things in conjunction with the hsv, but the hsv is my main issue right now. other than the obs, i don't seem to have any yeast or bacterial issues when no ob is present.

Finally, you should be aware of the important differences between genital HSV-1 and HSV-2. Nobody wants genital herpes, but if it happens, HSV-1 is definitely preferred! The frequency of recurrent outbreaks and the potential for transmission to future partners are much lower than for HSV-2. For more information, see the thread linked below. I hope this has helped.

Encephalitis is a complication only of HSV-1, not HSV-2; half of all Americans have HSV-1, yet there are only a few cases of HSV-1 encephalitis every year. Your chance of getting that complication is probably a lot lower than the chance you will die of a lightning strike (1 chance in 17,000 over the course of your lifetime, according to the National Safety Council); and much, much lower than the chance you will die of some accident within the next 12 months.

hello-i am a 28 year old female with hx of hsv-1 with frequent breakouts...just this year i've had 6 cold sores. I take oral valtrex if i feel the prodrome and this really helps shorten the duration. Recently, i became sexually involved with male partner, HSV-2 positive x 7 years, outbreak-free x 3 years and on daily suppressive therapy. We have had unprotected sex so I know I am at risk. My question is: Is there any benefit or harm in going on suppressive therapy myself.

is there a way to prevent viral encephalitis? why is it so deadly? is it because most people infected with HSV 1 dont even know it and have no idea about viral encephalitis and over look the symptoms? and what ARE the symptoms of viral encephalitis?

Also, it is conceivable that you now have a new HSV-2 infection, on top of the previously documented HSV-1. Herpes due to HSV-1 doesn't usually recur so soon. Having a new HSV-2 infection is unlikely, but it still is worth checking out to be certain. Return to the clinic as fast as possible -- today if they are open on Saturdays, or for sure on Monday. Having said all that, herpes outbreaks often vary in severity.

Acyclovir resistant hsv encephalitis

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