Dear Mrsrobert, welcome to the medhelp forum.
Aciphex or rabeprazole is proton pump inhibitor and tingling extremities can occur
with prolonged use. You need to inform your doctor immediately if you have been taking this drug for a while and have suggestive signs of Vitamin B12 deficiency like sore tongue, excessive weakness, tingling and numbness in the extremities due to decreased gastrointestinal absorption.