Aciphex janssen

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aciphex

475555 tn?1469304339 This could mean the trial is limited to certain countries like Ireland,and ?? and hasn't been listed yet? at clinicaltrials.gov CORK, Ireland, April 2, 2014 /PRNewswire/ -- Janssen R&D Ireland (Janssen) announced today that two Phase 3 trials are recruiting patients to examine the efficacy and safety of the NS3/4A protease inhibitor simeprevir in combination with the nucleotide inhibitor sofosbuvir for the treatment of chronic genotype 1 hepatitis C virus http://www.prnewswire.
Avatar f tn My husband was originally on Aciphex, but placed on Nexium after our insurance stopped covering aciphex and he was miserable. Aciphex has always worked so much better for him. Finally, after a year of misery he's back on aciphex and so much happier. I hope it works as well for you.
Avatar m tn Which, incidentally, stopped when I stopped taking the aciphex. Shortly after taking the aciphex I started experiencing symptoms of GERD. I still have the GERD to this day - some days its worse than others. I connect a straight line between the taking of aciphex and the development of GERD. Is this a reasonable conclusion? or is there some other more likely explanation?
Avatar f tn pylori bacteria in the digestive tract. The irony is, if you have ulcers and take Aciphex alone, the Aciphex could make the symptoms worse. Clearly something changed after taking the antibiotics, and now your ally in heartburn control has become your enemy. It might be worth getting back to your physician on this one, since antibiotics can often be a "swinging door", killing some bacteria while making it easier for other bacteria to get through that otherwise wouldn't have.
Avatar m tn Food and Drug Administration (FDA) has granted Priority Review to the New Drug Application (NDA) by Janssen for simeprevir (TMC435), an investigational NS3/4A protease inhibitor administered as a 150 mg capsule once daily with pegylated interferon and ribavirin for the treatment of genotype 1 chronic hepatitis C in adult patients with compensated liver disease.
Avatar n tn Since then I am taking Acid suppressants such as Nexium and Aciphex as prescribed by my doctor. I also underwent Endoscopy and Biopsy, Abdominal Ultrasound, X-Ray and Blood test . All the tests came normal except they found H-Pilory infection and I took antibiotics and subsequent Stool test for H-Pilory showed negative. I am still having all the above discomforts which is going on for 5 months. I normally eat very healthy and I am following a strict diet since this problem started.
Avatar n tn Has anyone tried Zegerid? So far I have tried Prevacid, Aciphex, Prilosec,Protonix, and Nexium. Aciphex gave me bad side effects and Nexium made my reflux symptoms worse. Prilosec did absolutely nothing for me. I was successfully treated for H. Pylori in Nov 07. Since then I have been suffering from Water Brash and now heartburn. I don't know where to turn. My GI now wants me to take Zegerid(isn't this med just like Prilosec with sodium?).
Avatar m tn Sense Simeprevir is another PI with about the same results as the other 2 I'm not sure a doctor would even recommend a prior failure even attempt it. Besides that it seems to be interferon just doesn't work for you. If it was me and I needed to treat right away I would ask about going off label and treat all oral using both of them, Sofo and simeprevir.
198506 tn?1251156915 I was diagnosed with silent reflux on 2/6/08 and prescribed Aciphex. The ENT diagnosed the reflux through an endoscopy I think it's called...he threaded a fiber optic camera through my nostril and down my throat. He said my throat was swollen and red and that I had vocal cord nodules. I had no symptoms of GERD and went to the ENT because I had a near constant feeling of throat contriction. A previous Barrium swallow showed no GERD.
Avatar m tn told no I am not fine, one area no concern, other area metaplasia, was I still taking the Aciphex. I have gone back on the Aciphex but am terrified after reading on websites that I did the wrong thing. Endoscopy only done originally because I had still unexplained/diagnosis following three days of diarrhea, cramping, dehydration. On antibiotiic, H pylori ruled out. History of GERD, hiatal hernia. Control symptoms with diet, OTC Gaviscon.
Avatar n tn I have been on Aciphex 20 since 2007, with instant results. After changing Health Ins. , I am told by the current insurer that they won't cover Aciphex. I must go thru a step program, starting with Nexium, which my Doctor dosed at 40 mg instead of 20 mg, saying Nexium didn't come in 20 and the 40mg of Nexium is comparable to the 20 mg Aciphex . Questions: (1) Is the above true? (2) Are the side effects the same, and (3) What's the difference between the two.
Avatar f tn I've taken Aciphex for over 10 years for extreme GERD. Since all the new studues came out about it being so bad long term, I decided to try and get off it. I'm down from 20mg a day to 20mg every 3-4 days. I've weaned over the last 2 months, had horrible rebound and can't get passed this stage. I have bad stomach pains, diarrhea, nausea. I'm supplementing with Tums currently. Any helpful advice is appreciated. I'm ready to give up.
Avatar m tn Wow this is indeed great news and the fact that they partnered with Janssen... I may be asking some more questions on if I qualify for this soon!
Avatar f tn I have for the past 10 years been on Aciphex 20mg for to much acid in my stomache, I was at 4 times the normal amount but now I have about 7 times to normal amount I have been taking 2 aciphex pills in the am and 1 in the evening. When I had my last scope I also had alot of irritation and alot of stomache polyps. I have latlely been having alot of diarreha about 2 hours after I eat and I'm generally not feeling well.
Avatar m tn 22, 2013 /PRNewswire/ -- Janssen Therapeutics, Division of Janssen Products, LP (Janssen), announced today the U.S. Food and Drug Administration (FDA) has approved OLYSIO™ (simeprevir), an NS3/4A protease inhibitor, for the treatment of chronic hepatitis C infection as part of an antiviral treatment regimen in combination with pegylated interferon and ribavirin in genotype 1 infected adults with compensated liver disease, including cirrhosis.
Avatar m tn ARWR) collaborator Janssen Pharmaceuticals, Inc., one of the Janssen Pharmaceutical Companies of Johnson & Johnson, presented clinical data from REEF-1, a Phase 2b study of different combination regimens, including JNJ-73763989 (JNJ-3989), formerly called ARO-HBV, and/or JNJ-56136379 (JNJ-6379), and a nucleos(t)ide analog (NA) for the treatment of chronic hepatitis B virus infection (CHB).
Avatar m tn Always nice to hear when a new medicine comes out for this problem we have Medivir AB (OMX: MVIR) today reports that Janssen Pharmaceutical R&D Ireland (Janssen) has been informed by the Japanese Ministry of Health, Labour and Welfare (MHLW) that simeprevir has been approved for the treatment of genotype 1 chronic hepatitis C virus (HCV) infection. "The approval in Japan is a very important step in providing patients with new treatment options.
Avatar m tn ), a leading RNA medicines company, announced today that preclinical data for a multi-siRNA treatment of Chronic Hepatitis B Virus (HBV), developed in collaboration with Janssen Pharmaceuticals, Inc., part of the Janssen Pharmaceutical Companies of Johnson & Johnson, will be presented in a poster at The Liver Meeting, the 67th Annual Meeting of the American Association for the Study of Liver Disease (AASLD) being held November 11-15, 2016, in Boston.
Avatar f tn well I am going to see my GI doc monday.. I have GERD and was taking AcipHex but had to stop when I found out I was pregnant.. so I am hoping it is just severe GERD related to that.. however, my lower back (flank, both sides) )is hurting more this morning, where the kidneys are.??? I am just wondering if the 2 can be related.. took pepto bismol last night and that seemed to help the stomach pain a little, but not completely... thanks for input!
Avatar m tn had mylanta and prilosec and the situation got improved.. doctor recommended aciphex and currently i am on that.. situation seems to get better but at times, the condition that I have something stuck in throat and a little difficulty to swallow flares up. Got a sore throat a couple of days back. but now it is better. feeling weak and has muscle pains occasionally.. any ideas? should i expect improvement only after a while? currently i am on the 15th day of taking aciphex...
Avatar n tn He recommended I go back on Aciphex or another PPI and to take Benadryl. This seems to make sense. I asked my GI about my hypersalivation problem but he did not know what the cause could be. After the Endoscopy and the H. Pylori visit, the GI doesn't wanted to be bothered. Anyone else have a similar experience?
Avatar n tn My husband is taking Aciphex for reflux, yet he continues to have stomach pain, not hearburn. He has recently had an upper GI and nothing was found. Nothing he takes orally helps the pain. What should he do if the specialist can't find his problem.
Avatar n tn when I was first diagnosed with Barretts I was taking aciphex. Two years later when I went for a re-check endoscopy the gastrointerologist suggested that I go on nexium. He said he thought it worked better than aciphex. Well about 8 weeks into the nexium I was getting great pains, I thought my desease was getting worse. I went back to the Dr. and asked to be put back on the aciphex. I beleive those pains were a side effect of the nexium.
Avatar m tn I was dx a few months back. Take advair twice a day (was taking singulair too, but it gave me a headache) & take aciphex daily for gerd. the aciphex has helped w/ the coughing some, but i still cough a good bit...sometimes to the point of dizziness. If I laugh, I cough. Any suggestions?
179856 tn?1333547362 The notes are secured by $155 million in success-based payments that Vertex is eligible to receive from Janssen Pharmaceutica. The milestones are linked to filing, approval, and launch of telaprevir in Europe. Separately, Vertex will receive roughly $35 million in cash for the sale of rights to an additional $95 million in future milestone fees tied only to the launch of telaprevir in Europe.