I started the Depo shots in April of 05, and i had the worst experience. Other than kidney stones
. My last shot was around May or June of 06. my last period was right before i started the shots. Within the first week of the first shot, I had such bad mood swings. I would cry, uncontrollably over nothing, all the time. My eating was all out of whack, there were days I couldn't stop eating and then days that I couldn't eat at all.